Reeler Mouse

We ask that you provide contact information, and agree to give credit to the Duke Center for In Vivo Microscopy for any written or oral presentation using data from this site. Please use the following acknowledgement: Imaging data provided by the Duke Center for In Vivo Microscopy NIH/NIBIB (P41 EB015897).

cortical and hippocampal layers

Supplementary Figure 5. The neocortical layers thickness was measured in the primary somatosensory cortex of the wild type (A) and homozygous Reeler mutant mouse (B), at the approximate level -2.1 mm from bregma (Hof et al., 2000), and found to be smaller in the mutant compared to the WT. In the CA1 region of the hippocampus  the pyramidal cell layers  occupied a larger area in the Relnrl/rl mouse compared to the WT, while the stratum radiatum was thinner. In the dentate gyrus the upper blade of the molecular cell layer was thinner, while the upper blade of the granular cell layer was wider in the mutant. In the CA3 region of the mutant the pyramidal cell layer was thicker compared to the WT.

Reeler Home

  • References
  • P.R. Hof, W.G. Young, F.E. Bloom, P.V. Belichenko, and M.R. Celio, 2000. "Comparative Cytoarchitectonic Atlas of the C57BL/6 and 129/Sv Mouse Brains". Elsevier.
  • George Paxinos and Keith B.J. Franklin, 2003. "The Mouse Brain in Stereotaxic Coordinates", Academic Press.

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