Imaging Tools for Powerful Insight

Founded in 1983, the CIVM is one of the oldest preclinical imaging laboratories in the country.

Diffusion tractography of the rat brain Courtesy, Evan Calabrese, MD,PhD

Welcome to the Duke Center for In Vivo Microscopy (CIVM).

The CIVM has two missions: our Small Animal Imaging Laboratory (SAIL) and Duke Imaging Innovation Laboratory (DIIL). At the heart of both is the development of innovative imaging tools and their application to important biomedical questions. We invite you to learn more here today and to contact us with questions or requests.

Small Animal Imaging Laboratory (SAIL)

CIVM, in collaboration with the Duke Pratt School of Engineering, provides state of the art imaging services for preclinical and basic science studies for the entire university. Featured equipment includes the 7T Bruker MRI System and the MILabs MicroSPECT System. Learn More

Duke Imaging Innovation Laboratory (DIIL)

With DIIL, CIVM is developing the next generation of imaging tools, leveraging the engineering expertise at Duke to push the technical boundaries of multimodal imaging. Featured equipment includes the 7 T Agilent MRI System and the 9.4T MRI System System. Learn More

Request a Project Collaboration

All project requests start here with your review of CIVM resources and rates and your submission of our online Project Request Form, either for SAIL or for DIIL. You'll be asked to provide the details of your project, including imaging needs, specific aims, timing and funding. Learn more and begin the project request form by choosing either SAIL or DIIL.

Recent News

Variability and heritability of mouse brain structure: Microscopic MRI atlases and connectomes for diverse strains

Genome-wide association studies have demonstrated significant links between human brain structure and common DNA… Read More

Nian Wang, Assistant Professor of Radiology wins an award for best picture in the BMC Research

Nian Wang, Assistant Professor of Radiology wins an award for best picture in the BMC Research In Progress.… Read More

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Recent Publications

Diffusion tractography of the rat knee at microscopic resolution

Wang N, Mirando AJ, Cofer G, Qi Y, Hilton MJ, Johnson GA. Diffusion tractography of the rat knee at microscopic resolution. Magn Reson Med. 2019 Jun;81(6):3775-3786. doi: 10.1002/mrm.27652. Epub 2019 Jan 22. PMID: 30671998. https://onlinelibrary.wiley.com/doi/abs/10.1002/mrm.27652

Cytoarchitecture of the mouse brain by high resolution diffusion magnetic resonance imaging

Wang, Nian, Leonard E. White, Yi Qi, Gary Cofer, G. Allan Johnson. "Cytoarchitecture of the mouse brain by high resolution diffusion magnetic resonance imaging." NeuroImage, Volume 216, 2020, 116876, ISSN 1053-8119 https://doi.org/10.1016/j.neuroimage.2020.116876.

Characterization complex collagen fiber architecture in knee joint using high-resolution diffusion imaging

Wang, Nian, Anthony J. Mirando, Gary Cofer, Yi Qi, Matthew J. Hilton, and G Allan Johnson. “Characterization complex collagen fiber architecture in knee joint using high-resolution diffusion imaging.” Magn Reson Med, January 21, 2020. https://doi.org/10.1002/mrm.28181.

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