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Contact Sally Zimney 919 684-7758 for copies or other publication information

journal articles/books: 2013 2012 2011 2010 2009 2008 2007  2006  2005 2004 2003 2002 2001 2000 1999 1998  1997  pre-1997 publications

Depending on copyright issues, links to NIH PubMedCentral (Free PMC Article) are available, and some availability through the publisher may be limited by institutional access.

These publications are associated with our Core faculty, students, collaborations or service projects, as well as those that resulted from sharing of data or figures.

See the links for SHARED DATA (listed as Supplements) for access to data from studies associated with the manuscript, or check this consolidated LIST OF SHARED DATA

20102013

A Badea, GA Johnson Magnetic resonance microscopy. Series: Studies in Health Technology and Informatics 2013;185:153-84. IOS Press Ebooks, 978-1-61499-239-4 (print) | 978-1-61499-240-0

C Badea, L Hedlund, GA Johnson, A LabVIEW platform for preclinical imaging using digital subtraction angiography and micro-CT, Journal of Medical Engineering Volume 2013, Article ID 581617, 1-13. Open access

R Bhavane, C Badea, KB Ghaghada, D Clark, D Vela, Anoosha Moturu, Ananth Annapragada, GA Johnson, JT Willerson, A Annapragada, Dual-energy computed tomography imaging of atherosclerotic plaques in a mouse model using a liposomal-iodine nanoparticle contrast agent, Circ Cardiovasc Imaging. 2013 Mar 1;6(2):285-94. online supplement (from journal)

E Calabrese, GA Johnson, C Watson, An ontology-based segmentation scheme for tracking postnatal changes in the developing rodent brain with MRI, Neuroimage, 67:375-384, 2013 Feb 11, Guide to MRH-based segmentation of all 26 structures available from the Neuroscience Lexicon wiki and online Supplement, PMCID: PMC3551262, if have access through Science Direct

E Calabrese, A Badea, C Watson, GA Johnson, A quantitative magnetic resonance histology atlas of postnatal rat brain development with regional estimates of growth and variability, NeuroImage 67:375-384, 2013 Feb 11, Supplement, if have access-Science Direct, NIHMSID#439248 PMC submission by journal

DP Clark, A Badea, GA Johnson, CT Badea, Constructing a 4D murine cardiac micro-CT atlas for automated segmentation and phenotyping applications, Proceedings of SPIE, paper 8669-60, 2013.

DP Clark, SM Johnston, GA Johnson, CT Badea, The effect of cross-scatter correction on the performance of dual energy micro-CT, Proceedings of SPIE, 8668, 86684T, 2013.

DP Clark, K Ghaghada, EJ Moding, DG Kirsch, CT Badea, In vivo characterization of tumor vasculature using iodine and gold nanoparticles and dual energy micro-CT, Phys Med Biol 58(6):1683-1704, 2013 March 21. Supplement NIHMSID#449989 PMC submission by journal

C Constantinides, Chapter 14: Study of the Murine Cardiac Mechanical Function Using Magnetic Resonance Imaging: The Current Status, Challenges, and Future Perspectives, in Practical Applications in Biomedical Engineering, (Eds. Eduardo L. Pereira, M. Naves , Alcimar B. Soares), ISBN 978-953-51-0924-2, January 9, 2013, InTech, 410 p. Open access

C Constantinides (2013). Murine Cardiac Hemodynamics: The Development and Use of Invasive Catheters, and the Emergence of New Methodologies, Herzaki (Ed), Hemodynamics: Monitoring, Theory and Applications, New York: NOVA Publications (Chapter 3, pp. 25-48). http://lbi-cy.com/?page_id=80

E Gyengesi, E Calabrese, MC Sherrier, GA Johnson, G Paxinos, C Watson. Semi-automated 3D segmentation of major tracts in the rat brain: comparing DTI with standard histological methods. Brain Struct Funct. 2013 Mar 1. [Epub ahead of print]

C Liu, W Li, Imaging neural architecture of the brain based on its multipole magnetic response. NeuroImage 67 193-202, 2013. PMC submission by journal

P Pandit, SM Johnston, Y Qi, J Story, R Nelson, GA Johnson, The utility of microCT and MRI in the assessment of longitudinal growth of liver metastases in a preclinical model of colon carcinoma, Academic Radiology 20(4): 430-439, April 2013, NIHMS 421806, if have access - Science Direct

BA Perez, AP Ghafoori, C-L Lee, SM Johnston, Y Li, JG Moroshek, Y Ma, S Mukherjee, Y Kim, CT Badea, DG Kirsch, Assessing the radiation response of lung cancer with different gene mutations using genetically engineered mice, Frontiers in Oncoogy, Volume 3, article 72, April 2, 2013. doi: 10.3389/fonc.2013.00072

E Subashi, G Cofer, J MacFall, Y Qi, GA Johnson, A comparison of keyhole strategies for high spatial and temporal resolution 4D contrast-enhanced MRI in small animal tumor models, Medical Physics 40(2): 022304, 2013. PMCID: PMC3562278

In Press - PubMedCentral in process

T Pierce, E Calabrese, LE White, SD Chen, SR Platt, James Provenzale, Segmentation of the canine corpus callosum using diffusion tensor imaging tractography, American Journal of Roentgenology, in press 2013

20102012

A Badea, GA Johnson, Review article: Magnetic resonance microscopy, Analytical Cellular Pathology 35(4):205-227, 2012. PMCID:PMC22142643

A Badea, S Gewalt, BB Avants, JJ Cook, GA Johnson. Quantitative mouse brain phenotyping based on single and multispectral MR protocols. NeuroImage 63 1633-1645, 2012. NIHMS#396334

BT Antonsen, Y Jiang, J Veraart, H Qu, HP Nguyen, J Sijbers, S von Hörsten, GA Johnson, TB Leergaard, Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats. Brain Structure and Function 2012 May 23. Open access

C Badea, X Guo, D Clark, S Johnston, C Marshall, C Piantadosi, Dual energy micro-CT of the rodent lung, American Journal of Physiology - Lung Cellular and Molecular Physiology 302(10):L1088-1097, 2012. PMCID: PMC3362256

C Badea, KK Athreya, G Espinosa, DP Clark, AP Ghafoori, Y Yi, DG Kirsch, GA Johnson, A Annapragada, KB Ghaghada, Computed tomography imaging of primary lung cancer in mice using a liposomal-iodinated contrast agent, PLoS ONE 7(4): e34496, 2012 PMCID: PMC3317632 open access

CT Badea, X Guo, D Clark, SM Johnston, C Marshall, C Piantadosi. Lung imaging in rodents using dual energy micro-CT. Proceedings of SPIE 8317, 83171I, 2012

CT Badea, IN Stanton, SM Johnston, GA Johnson, MJ Therien. Investigations on x-ray luminescence CT for small animal imaging. Proceedings of SPIE 8313, 83130T, 2012 NIHMSID #421296

RC Bell, D Rogith, CW Johnson, CT Badea, KK Athreya, G Espinosa, D Clark, AP Ghafoori, Y Li, DG Kirsch, A Annapragada, K Ghaghada, Data analysis: Evaluation of nanoscale contrast agent enhanced CT scan to differentiate between benign and malignant lung cancer in mouse mode, American Medical Informatics Association (AMIA) Annual Symposium Proceedings Archive 2012:27-35, 2012, published online Nov 3 PMCID: PMC3540499

D Clark, GA Johnson, CT Badea, Denoising of 4D cardiac micro-CT data using median-centric bilateral filtration, Proceedings SPIE, Vol. 8314, 2012 NIHMSID #421306

D Clark, A Badea, Y Liu, GA Johnson, CT Badea. Registration-based segmentation of murine 4D cardiac micro-CT data using symmetric normalization. Physics in Medicine and Biology 57:6125-6145, 2012, PMC in process, Supplement

ZI Cleveland, HE Moller, LW Hedlund, JC Nouls, MS Freeman, Y Qi, B Driehuys, in vivo MR imaging of pulmonary perfusion and gas exchange in rats via continuous extracorporeal infusion of hyperpolarized 129Xe, PLoS ONE 7(2): e31306, 2012 PMCID: PMC3283644

C Constantinides, S Angeli, F Kossivas, P Ktorides, Underestimation of murine cardiac hemodynamics using invasive catheters: Errors, limitations, and remedies, Cardiovascular Engineering and Technology 3(2): 179-193, 2012

MT Davis, AM Loyd, H Shen, MH Mulroy, RW Nightingale, BS Myers, CD Bass, The mechanical and morphological properties of 6 year-old cranial bone, Journal of Biomechanics, 45(15): 2493–2498, 11 October 2012

B Driehuys, S Martinez-Jimenez, ZI Cleveland, GM Metz, DM Beaver, JC Nouls, SS Kaushik, et al., Chronic Obstructive Pulmonary Disease: Safety and tolerability of hyperpolarized 129Xe MR imaging in healthy volunteers and patients, Radiology 262(1):279-289, Jan 2012 article highlighted in Diagnostic Imaging, PMCID: PMC3244666

Y Feng, R Davis, WS Warren. Accessing long-lived nuclear singlet states between chemically equivalent spins without breaking symmetry. Nature Physics. 8: 831-837, 2012 published online Sept 16

X Guo, SM Johnston, Y Qi, GA Johnson, CT Badea, 4D micro-CT using fast prospective gating, Physics in Medicine and Biology, 57(1): 257–271, 2012

X Guo, SM Johnston, GA Johnson, CT Badea, A comparison of sampling strategies, Proceedings SPIE, Vol. 8313, 2 March 2012

GP Howles, Y Qi, SJ Rosenzweig, KR Nightingale, GA Johnson, Functional neuroimaging using ultrasonic blood-brain barrier disruption and manganese-enhanced MRI, Journal of Visualized Experiments (JoVE), e4055, DOI: 10.3791/4055, 2012

GA Johnson, E Calabrese, A Badea, G Paxinos, C Watson, A multidimensional magnetic resonance histology atlas of the Wistar rat brain, Neuroimage 62(3): 1848–1856, 2012. PMCID: PMC3408821 Supplement FIGURE CHOSEN FOR ISSUE COVER

GA Johnson, B Adcock, M Sherrier, A Badea, Virtual Mouse Brain, iPad App Store, October, 2012

SM Johnston, CT Badea, A spectral calibration technique for x-ray CT, Proceedings SPIE 8313: 831333, March 2012

SM Johnston, GA Johnson, CT Badea, Temporal and spectral imaging with micro-CT. Medical Physics, 39(8): 4943-4968, 2012. PMCID: PMC3416878 Supplemental material

B Li, Y Cheng, J Liu, C Yi, AS Brown, H Yuan, T Vo-Dinh, MC Fischer, WS Warren. Direct optical imaging of graphene in vitro by nonlinear femtosecond laser spectral reshaping. Nano Lett. 2012 Nov 14;12(11):5936-40. W Li, B Wu, AV Avram, C Liu, Magnetic susceptibility anisotropy of human brain in vivo and its molecular underpinnings. Neuroimage 2012; 59(3): 2088-2097. PMCID: PMC3254777

R Lipinski, P Hammond; S O'Leary-Moore; J Ament; S Pecevich; Y Jiang; F Budin; S Parnell; M Suttie; E Godin; J Everson; D Dehart; I Oguz; H Holloway; M Styner; GA Johnson; K Sulik, Ethanol-induced face-brain dysmorphology patterns are correlative and exposure-stage dependent, PLoS ONE 7(8): e43067, 2012. doi:10.1371/journal.pone.0043067 PMCID: PMC3425589 or open access through journal. Press release about this article

C Liu W Li, B Wu, Y Jiang, GA Johnson, 3D fiber tractography with susceptibility tensor imaging, Neuroimage.59(2):1290-1298, 2012. PMCID: PMC3235503

Y Loo, CL Grigsby, YJ Yamanaka, MK Chellappan, X Jiang, HQ Mao, KW Leong, Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models, J Control Release. 2012 May 30;160(1):48-56. doi: 10.1016/j.jconrel.2012.01.041. Epub 2012 Feb 3. PMCID: PMC3473091

EJ Moding, DP Clark, Y Qi, Y Li, Y Ma, K Ghaghada, GA Johnson, DG Kirsch, CT Badea, Dual energy micro-CT imaging of radiation-induced vascular changes in primary mouse sarcomas, ROB-D-12-01030, International Journal of Radiation Oncology*Biology*Physics, 2012 Nov 1. pii: S0360-3016(12)03635-8. doi: 10.1016/j.ijrobp.2012.09.027 Epub ahead of print Science Direct

D Perperidis, E Bucholz, GA Johnson, C Constantinides, Morphological studies of the murine heart based on probabilistic and statistical atlases. Comput Med Imaging Graph. 36 (2012) 119-129, 2012 PMCID: PMC21820867

FE Robles, JW Wilson, MC Fischer, WS Warren. Phasor analysis for nonlinear pump-probe microscopy. Optics Express. 2012;20(15):17082-17092. OpticsInfoBase

P Samineni, A deCruz, TE Villafaña, WS Warren, MC Fischer, Pump-probe imaging of historical pigments used in paintings. Opt Lett. 2012;37(8):1310-1312.

P Samineni, B Li, JW Wilson, WS Warren, MC Fischer, Cross-phase modulation imaging. Opt Lett. 2012b;37(5):800-802. PMCID: PMC3371360

AC Thomas, SS Kaushik, J Nouls, EN Potts, DM Slipetz, WM Foster, B Driehuys, Effects of corticosteroid treatment on airway inflammation, mechanics, and hyperpolarized 3He MR imaging in an allergic mouse model, J Appl Physiol 112:1437-1444, 2012 PMCID: PMC3362235. Invited editorial about this article—“Editor’s Picks” Tilo Winkler, Jose G. Venegas, Are all aiways equal? J Appl Physiol 112:1437-1444, 2012.

RS Virgincar, ZI Cleveland, SS Kaushik, MS Freeman, J Nouls, GP Cofer, S Martinez-Jimenez, M He, M Kraft, J Wolberg, HP McAdams, B Driehuys, Quantitative analysis of hyperpolarized 129Xe ventilation imaging in healthy volunteers and subjects with chronic obstructive pulmonary disease, NMR in Biomedicine, 2012 Oct 13. doi: 10.1002/nbm.2880. [Epub ahead of print] PMCID: PMC3362235

JM Ward, SA Elmore, JF Foley, Pathology methods for the evaluation of embryonic and perinatal developmental defects and lethality in genetically engineered mice. Vet Pathol 49(1):71-84, 2012; uses CIVM figure

JW Wilson, P Samineni, WS Warren, MC Fischer. Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope. Biomed Opt Express. 2012;3(5):854-862. PMCID: PMC3342192

T Wu, MH Bae, M Zhang, R Pan, A Badea, A prior feature SVM-MRF based method for mouse brain segmentation. Neuroimage. 59(3):2298-306, 2012 Feb 1 PMCID: PMC3254777

L Xie, R Cianciol, B Hulette, H Won Lee, Y Qi, G Cofer, GA Johnson, Magnetic resonance histology of age-related nephropathy in the Sprague Dawley rat, Toxicologic Pathology 40(5):764-778, 2012 Supplement PMCID: PMC22504322

X Zhang, CT Badea Highly efficient detection in fluorescence tomography of quantum dots using time-gated acquisition and ultrafast pulsed laser, Proceedings of SPIE, 7896: 78962W 2012

20102011

CT Badea, LW Helund, J Cook, BR Berridge, GA Johnson, Micro-CT imaging assessment of dobutamine-induced cardiac stress in rats, J Pharma Tox Methods 63(1):24-29, 2011, Free PMC article, or institutional access, Elsevier full text article

CT Badea, SM Johnston, Y Qi, K Ghaghada, GA Johnson, Dual-energy micro-CT imaging for differentiation of iodine- and gold-based nanoparticles temporal and spectral reconstruction algorithms for x-ray CT, Proc. SPIE 7961, 79611X, 2011

CT Badea, K Ghaghada, G Espinosa, L Strong, A Annapragada, Multi-modality PET-CT imaging of breast cancer in an animal model using nanoparticle x-ray contrast agent and 18F-FDG, Proc. SPIE 7965, 796511, 2011

CT Badea, SM Johnston, Y Qi, GA Johnson, 4D micro-CT for cardiac and perfusion applications with view under sampling, Phys Med Biol 56(11): 3351–3369, 2011, if have access, Free text from IOP Publishing

B Bolon, RH Garman, HJ Gundersen, GA Johnson, W Kaufmann, G Krinke, PB Little, SL Makris, RD Mellon, Sulik KK, Jensen K. Continuing Education Course #3: Current Practices and Future Trends in Neuropathology Assessment for Developmental Neurotoxicity Testing, Toxicol Path 39(1): 289-293, 2011, if have access, Free full text from SAGE Publications

DM Bowden, GA Johnson, L Zaborsky, WD. Green, E Moore, A Badea, et al. A symmetrical Waxholm canonical mouse brain for NeuroMaps, J Neurosci Methods 195(2): 170-175, 15, 2011, PMCID: PMC3103134, if access available, Elsevier Full Text Article

C Constantinides, Case Study: MRI coil improvement for cardiac imaging in mice, in REMCOM Inc., 2/16/2011 Newsletter, State College, PA, web site

C Constantinides, R Mean, BJ Janssen, Effects of isoflurane anesthesia on the cardiovascular function of the C57BL/6 mouse, ILAR Journal 52:e21-e31, 2011. PMCID: PMC3508701

KB Ghaghada, CT Badea, L Karumbaiah, N Fettig, RV Bellamkonda, GA Johnson, A Annapragada, Evaluation of tumor microenvironment in an animal model using a nanoparticle contrast agent in computed tomography imaging, Academic Radiology 18(1):20-30, 1, 2011, PMCID: PMC3016875

M Hawrylycz, RA Baldock, A Burger, T Hashikawa, GA Johnson, et al. Digital atlasing and standardization in the mouse brain, PLoS Computational Biology 7(2): e1001065, 2011. PMCID: PMC3033370

Y Jiang, GA Johnson, Microscopic diffusion tensor atlas of the mouse brain, Neuroimage 56(3): 1235-1243, 2011 Supplemental data, if have access, Elsevier Full Text Article

GA Johnson, A Badea, Y Jiang, Quantitative neuromorphometry using magnetic resonance histology, Toxicol Path 39(1):85-91, 2011, PMCID: PMC3073322, if have access, Full text from SAGE Publications

SM Johnston, CT Badea, Temporal and spectral reconstruction algorithms for x-ray CT, Proc. SPIE 7961, 79611U, 2011. If have access, available from SPIE digital library

SS Kaushik, ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls, M Kraft, J Wolber, KT Kelly, W Auffermann, HP McAdams, B Driehuys, Diffusion weighted imaging of hyperpolarized 129Xe in patients with chronic obstructive pulmonary disease, Magn Reson Med 65(4):1154-1165, 2011, if have access, Free text Wiley Online Library

C Liu, W Li; GA Johnson; B Wu, High-field (9.4 T) MRI of brain dysmyelination, Neuroimage 56(3):930-938, 2011, if have access, Elsevier Full Text Article

TE Matthews, IR Piletic, MA Selim, MJ Simpson, WS Warren. Pump-probe imaging differentiates melanoma from melanocytic nevi. Sci Transl Med. 2011;3(71):71ra15. PMCID: PMC3371363

TE Matthews, JW Wilson, S Degan, MJ Simpson, JY Jin, JY Zhang, et al. In vivo and ex vivo epi-mode pump-probe imaging of melanin and microvasculature. Biomed Opt Express. 2011;2(6):1576-1583. PMCID: PMC3114225

NCI Cancer Bulletin, Imaging Boot Camp for Cancer Researchers (participation by Dr. Cristian Badea)

J Nouls, M Fanarjian, L Hedlund, A constant-volume ventilator and gas recapture system for hyperpolarized gas MRI of mouse and rat lungs, Concepts in Magn Reson Part B: Magn Reson Eng, 39B(2): 78–88, 2011, Supplemental data

SK O’Leary-Moore, SE Parnell, RJ Lipinski, KK Sulik, Magnetic Resonance-Based Imaging in Animal Models of Fetal Alcohol Spectrum Disorder, Neuropsychology Review 21(2): 167-185, 2011, if have access, SpringerLink full text article

P Pandit, Y Qi, KF King, GA Johnson, Reduction of artifacts in T2-weighted PROPELLER in high-field preclinical imaging, Magn Reson Med 65(2):538-543, 2011, PMCID: PMC3026877. If have access, Free text from Wiley Online Library

RA Peterson (co-chair), KL Gabrielson (co-chair), GA Johnson, MG Pomper, RW Coatney, CT Winkelmann, Continuing Education Course #1: Non-Invasive Imaging as a Problem-Solving Tool and Translational Biomarker Strategy in Toxicologic Pathology, Toxicol Path 39(1):267-272, 2011. If have access, Full text from SAGE Publications

M Poot, A Badea, RW Williams, MJ Kas, Identifying human disease genes through cross-species gene mapping of evolutionary conserved processes, PLoS One, May 4;6(5):e18612, 2011, Free PMC article or directly from online journal

S Rajagopal, J Kovacs, C Badea, GA Johnson, HA Rockman, CA Piantadosi, RJ Lefkowitz, Beta-arrestins regulate signaling by bone morphogenetic protein type ii receptor in pulmonary arterial hypertension, J Am Coll Cardiol, April 5, 2011; 57: E2046, ACC Special Session, Young Investigators Award Competition: Molecular and Cellular Cardiology, April 3, 2011

AC Thomas, JC Nouls, B Driehuys, JW Voltz, B Fubara, J Foley, JA Bradbury, DC Zeldin, Ventilation defects observed with hyperpolarized 3He magnetic resonance imaging in a mouse model of acute lung injury, Am J Respir Cell Mol Biol 44(5):648-54, 2011, data supplement, PMCID: PMC3095984, if have access Journal text available

X Zhang, CT Badea, Highly efficient detection in fluorescence tomography of quantum dots using time-gated acquisition and ultrafast pulsed laser, Proc SPIE, Jan 23;7896. pii: 78962W, 2011, Free PMC Article

X Zhang, C Badea, G Hood, A Wetzel, Y Qi, J Stiles, GA Johnson, High-resolution reconstruction of fluorescent inclusions in mouse thorax using anatomically guided sampling and parallel Monte Carlo computing, Biomedical Optics Express 2(9): 2449-2460, 1 September 2011. Free PMC article

W Zheng, ZI, Cleveland, HE Möller, B Driehuys. Gradient-induced longitudinal relaxation of hyperpolarized noble gases in the fringe fields of superconducting magnets used for MR, J Magn Reson 208(2):284-290, 2011. If have access, Elsevier full text article

20102010 

A Badea, GA Johnson, JL Jankowsky, Remote sites of structural atrophy predict later amyloid formation in a mouse model of Alzheimer's disease, Neuroimage 50(2): 416–427, 2010. Supplemental data Free PMC article or if have access, through Elsevier full text article

CT Badea, SM Johnston, E Subashi, Y Qi, LW Hedlund, GA Johnson, Lung perfusion imaging in small animals using 4D micro-CT at heartbeat temporal resolution, Medical Physics 37(1): 54-62, Jan. 2010. Free PMC article

MH Bae, T Wu, R Pan, Mix-ratio sampling: Classifying multiclass imbalanced mouse brain images using support vector machine, Expert Systems with Applications 37(7): 4955-4965, July 2010. Free PMC article

RT Branca, Z Cleveland, B Fubara, CSSR Kumar, RR Maronpot, C Leuschner, WS Warren, B Driehuys, Molecular MRI for sensitive and specific detection of lung metastases, Proc Natl Acad Sci U S A. Feb 23;107(8):3693-3697, 2010, from journal Free article

C Brinegar, SS Schmitter, NN Mistry, GA Johnson, Z-P Liang, Improving temporal resolution of pulmonary perfusion imaging in rats using the PSF model, Magn Reson Med 64:1162–1170, 2010. Free text through Wiley Online Library

E Bucholz, K Ghaghada, Y Qi, S Mukundan, HA Rockman, GA Johnson, Cardiovascular phenotyping of the mouse heart using a 4D radial acquisition and liposomal Gd-DTPA-BMA, Magn Reson Med Apr63(4):979-987, 2010. Supplemental data Free PMC article

ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls, SS Kaushik, M Kraft, J Wolber, KT Kelly, HP McAdams, B Driehuys, Hyperpolarized 129Xe MR imaging of alveolar gas uptake in humans, PLoS ONE 5(8): e12192, 2010 Free article

C Constantinides, S Gkagkarellis, S Angeli, G Cofer, A novel spiral radiofrequency coil for high field mouse cardiac imaging, Remcom Inc. web site Conference Proceedings, 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'10), Buenos Aires, Argentina, September 1-4, 2010. Conf Proc IEEE Eng Med Biol Soc. 2010;1:6657-61

C Constantinides, Case Study: MRI coil improvement for cardiac imaging in mice, REMCOM newsletter

EA Godin, SK O’Leary-Moore, AA Kahn, JJ Ament, SE Parnell, DB Dehart, BW Johnson, GA Johnson, MS Styner, KK Sulik, Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 7; Alcohol Clin Exp Res. Jan;34(1):98-111, 2010. If have access, available through Wiley Online Library

GP Howles, Y Qi, GA Johnson, Ultrasonic disruption of the blood-brain barrier enables in vivo functional mapping of the mouse barrel field cortex with manganese-enhanced MRI, Neuroimage 50(4):1464-1471, 2010, Free PMC article

GP Howles, KF Bing, Y Qi, SJ Rosenzweig, KR Nightingale, GA Johnson, Contrast-enhanced in vivo magnetic resonance microscopy of the mouse brain enabled by non-invasive opening of the blood-brain barrier with ultrasound, Magn Reson Med, 64(4):995-1004. 2010. PMCID: PMC2950102 or if have access through Wiley Online Library

Y Jiang, GA Johnson, Microscopic diffusion tensor imaging of the mouse brain, NeuroImage, Apr 1;50(2):465-471, 2010. Supplemental data Free PMC article or available through Elsevier Full Text Article

GA Johnson, A Badea, J Brandenburg, G Cofer, B Fubara, S Liu, J Nissanov, Waxholm Space: An image-based reference for coordinating mouse brain research, Neuroimage, 53(2): 365-372, 2010, Supplemental data PMCID: PMC2930145, or if have access available through Elsevier Full Text Article

Photonics.com, Online Atlas Shows Brain in Sharp Detail

ScienceDaily: Major Step Taken Toward an Open and Shared Digital Brain Atlasing Framework (Feb. 8, 2011)

SciMed - Neuroscience TS-SI NEWS SERVICE, 27 October 2010: Detailed images upgrade Online Mouse Brain Atlas

SM Johnston, BA Perez, DG Kirsch, CT Badea, Phase-selective image reconstruction of the lungs in small animals using micro-CT; Medical Imaging 2010: Physics of Medical Imaging, Proc SPIE 7622, 76223G-1-9, 2010, Free PMC article

SM Johnston, GA Johnson, CT Badea, GPU-based iterative reconstruction with total variation minimization for micro-CT, Proc. SPIE 7622, 762238, 2010. If have access, available through SPIE Digital Library

Lipinski RJ, Godin EA, O’leary-Moore SK, Parnell SE, Sulik KK, Genesis of teratogen-induced holoprosencephaly in mice, Am J Med Genetics, Part C 154C: 29-42, 2010, Free PMC article or if have access from Wiley Online Library

RJ Lipinski, C Song, KK Sulik, et al. Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications. Birth Defects Res A Clin Mol Teratol 88(4):232-240, 2010. Free PMC article or if have access from Wiley Online Library

NN Mistry, Y Qi, LW Hedlund, GA Johnson, Ventilation / perfusion imaging in a rat model of airway obstruction, Magn Reson Med 63 (3):728–735, 2010. Free PMC article

NN Mistry, A Thomas, SS Kaushik, GA Johnson, B Driehuys, Quantitative analysis of hyperpolarized 3He ventilation changes in mice challenged with Methacholine, Magn Reson Med 63:658–666, 2010. Free PMC article or if have access, available through Wiley Online Library

SK O'Leary-Moore, SE Parnell, EA Godin, DB Dehart, JJ Ament, AA Khan, GA Johnson, MA Styner, KK Sulik, Magnetic resonance microscopy-based analyses of the brains of normal and ethanol-exposed fetal mice. Birth Defects Res A Clin Mol Teratol 88(11):953-64, 2010. If have access, available through Wiley Online Library

P Pandit, Y Qi, K King, GA Johnson, Multi-shot PROPELLER for high-field preclinical MRI, Magn Reson Med, 64(1):47-53, 2010. If have access, free text from Wiley Online Library

A Petiet, GA Johnson, Active Staining of Mouse Embryos for Magnetic Resonance Microscopy. In: Hewitson Tim D & Darby Ian A (editors), Histology Protocols (Series: Methods in Molecular Biology), Springer-Humana Press. Totowa, NJ. USA, 611:141-149, (230 p) 2010. Free PMC article

2009

A Badea, RW Williams, GA Johnson, Genetic dissection of the mouse brain using high-field magnetic resonance microscopy, Neuroimage. 45(4):1067-1079, 2009. Free PMC article or if have access through Elsevier Full Text Article

A Badea, GA Johnson, R Williams, Genetic dissection of the mouse CNS using magnetic resonance microscopy, invited paper: Current Opinion in Neurology 22:379-386, 2009, Free PMC article

CT Badea, SM Johnston, E Subashi, Y Qi, LW Hedlund, GA Johnson, Lung perfusion imaging in small animals using 4d micro-CT at heartbeat temporal resolution, Medical Physics 37(1): 54-62, 2010. Free PMC article

M Hyeok Bae, R Pan, T Wu, A Badea, Automated segmentation of mouse brain images using extended MRF, Neuroimage 46(3): 717-725, 2009, Free PMC article or if have access, through Elsevier Full Text Article

K Frinkley Bing, GP Howles, Y Qi, ML Palmeri, KR. Nightingale, Blood-brain barrier disruption using a diagnostic ultrasound scanner and DefinityŽ in mice, Ultrasound in Medicine and Biology, 35:1298-1308, 2009. Free PMC article or if have access through Elsevier Full Text Article

Z Cleveland, H Moeller, L Hedlund, B Driehuys, Continuously infusing hyperpolarized 129Xe into flowing aqueous solutions using hydrophobic gas exchange membranes, The Journal of Physical Chemistry B, 113(37): 12489-12499, 2009. Free PMC article or if have access through ACS Publications

B Driehuys, H Moeller, J Pollaro, Z Cleveland, LW Hedlund, Pulmonary perfusion and xenon gas exchange in rats: MR imaging with intravenous injection of hyperpolarized 129Xe , Radiology 252(2): 386-393, 2009. Free PMC article or final version Free from journal

GP Howles, JC Nouls, Y Qi, GA Johnson, Rapid production of specialized animal handling devices using computer-aided design and solid freeform fabrication, Journal of Magnetic Resonance Imaging, 30(2):466-471, 2009. Supplemental data Free PMC article

GP Howles, KB Ghaghada, Y Qi, S Mukundan, Jr., GA Johnson, High-resolution magnetic resonance angiography in the mouse using a nanoparticle blood-pool contrast agent, accepted/in press, Magn Reson Med 62(6): 1447-1456, 2009, Free PMC article

M Lin, CT Marshall, Y Qi, SM Johnston, CT Badea, CA Piantadosi, GA Johnson, Quantitative blood flow measurements in the small animal cardiopulmonary system using digital subtraction angiography, Medical Physics 36(11) 5347-5358, 2009. Free PMC article or available through Mendeley

A Mackenzie-Graham SK Tiwari-Woodruff, G Sharma, C Aguilar, KT Vo, LV Strickland, L Morales, B Fubara, M Martin, RE Jacobs, GA Johnson, AW Toga, RR Voskuhl, Purkinje cell loss in experimental autoimmune encephalomyelitis, NeuroImage, 48(4): 637-652, 2009. Free PMC article

SE Parnell, SK O'Leary Moore, EA Godin, DB Dehart, BW Johnson, GA Johnson, MA Styner, KK Sulik, Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8, Alcoholism: Clinical and Experimental Research 33(4): 1001-1011, 2009. Free PMC article or if available through Wiley Online Library

E Samei, RS Saunders, CT Badea, KB Ghaghada, LW Hedlund, Y Qi, H Yuan, RC Bentley, S Mukundan, Jr., GA Johnson, Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent, Intl J Nanomed 4: 277-282, 2009. Free PMC article or if have access through Dovepress

J Song, Yi Liu, SL Gewalt, G Cofer, GA Johnson, QH. Liu, Least-square NUFFT methods applied to 2-D and 3-D radially encoded MR image reconstruction, IEEE Trans Biomed Eng, 56(4):1134-1142, 2009. Free PMC article or if have access through IEEE Xplore Digital Library

AC Thomas, EN Potts, BT Chen, DM Slipetz, WMFoster, B Driehuys. A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized (3)He MRI, NMR Biomed. 22(5): 502-515, 2009, Free PMC article

X Zhang, C Badea, Effects of sampling strategy on image quality in noncontact panoramic fluorescence diffuse optical tomography for small animal imaging, Optics Express 17(7): 5125-5138, 2009. Free PMC article

X Zhang, C Badea, M Jacob, GA Johnson, Development of a noncontact 3-D fluorescence tomography system for small animal in vivo imaging, Proc SPIE 7191 Feb 16, 2009. Free PMC article

X Zhang, CT Badea, GA Johnson, Three-dimensional reconstruction in free-space whole-body fluorescence tomography of mice using optically reconstructed surface and and atlas anatomy, J Biomed Optics 14(6):064010, 2009 Free PMC article or if have access, through SPIE Digital Library

2008

C Badea, E Schreibmann, T Fox, A registration-based approach for cardiac micro-CT using combined prospective and retrospective gating, Medical Physics, 35(4): 1170-1179, 2008. Free PMC article or if have access, through journal

CT Badea, AW Wetzel, SM Pomerantz, N Mistry, D Nave, GA Johnson, Left ventricle volume measurements in cardiac micro-CT: the impact of radiation dose and contrast agent, Computerized Medical Imaging and Graphics, 32: 239-250, 2008. Free PMC article or if have access through Elsevier Full Text Article

CT Badea, M Drangova, DW Holdsworth, GA Johnson, In vivo small-animal imaging using micro-CT and digital subtraction angiography, Phys. Med. Biol. 53(19): R319-R350, 2008. Free PMC article

E Bucholz, J Song, GA Johnson, I Hancu, Multi-spectral imaging with three-dimensional rosette trajectories, Magn Reson Med, 59(3): 581-589, 2008. Free PMC article or if have access, through Wiley Online Library

E Bucholz, K Ghaghada, Y Qi, S Mukundan, GA Johnson, Four-dimensional MR microscopy of the mouse heart using radial acquisition and liposomal gadolinium contrast agent, Magn Reson Med, 60(1):111-118, 2008. Free PMC article Supplemental data or if have access, through Wiley Online Library

AF Chen, CM Davies, MD Lin, B Fermor, Oxidative DNA damage in osteoarthritic porcine articular cartilage, Journal of Cellular Physiology, J Cell Physiol. 2008 Dec;217(3):828-33, 2008. Free PMC article, or if have access, available through IOP Science

B Driehuys, J Nouls, A Badea, A Petiet, E Bucholz, K Ghagada, L Hedlund, Small-animal imaging with magnetic resonance microscopy, invited paper, ILAR Journal Noninvasive Bioimaging of Laboratory Animals 49(1):35-53, 2008. Free PMC article

B Driehuys, J Pollaro, GP Cofer, In vivo MRI using real-time production of hyperpolarized 129Xe, Magn Reson Med, 60(1):14-20, 2008. Free PMC article, or if have access, through Wiley Online Library

MM Goddeeris, S Rho, A Petiet, CL Davenport, GA Johnson, EN Meyers, J Klingensmith, Intracardiac septation requires hedgehog-dependent cellular contributions from outside the heart, Development 135(10):1887-95, May 2008. Supplemental data Free PMC article or if have access, through the journal

S Johnston, GA Johnson, C Badea, Geometric calibration for a dual tube/detector micro-CT system, Medical Physics 35(5): 1820-1829, May 2008. Free PMC article or if have access to journal

MD Lin, L Ning, CT Badea, GA Johnson, A high-precision contrast injector for small animal x-ray digital subtraction angiography, IEEE Trans on Biomed Eng, 55(3): 1082-1091, 2008. Free PMC article or if have access, available through IEEE XPlore

MD Lin, G Toncheva, G Nguyen, S Kim, CAnderson-Evans, GA Johnson, TT Yoshizumi. Application of MOSFET detectors in small animal digital subtraction angiography (DSA) dosimetry, Radiation Research, 170: 260-263, 2008. Free PMC article or if have access to Allen Press Full Text

NN Mistry, J Pollaro, J Song, GA Johnson, Pulmonary perfusion imaging in the rodent lung using dynamic contrast-enhanced MRI, Magn Reson Med, 59(2):289-297, Jan 28, 2008. Free PMC article or if have access, through Wiley Online Library

JC Nouls, MG Izenson, HP Greeley, GA Johnson, A superconducting volume coil for magnetic resonance microscopy of the mouse brain, Journal of Magnetic Resonance Imaging 191(2): 231-238, 2008, Free PMC article and if have access, through Elsevier Full Text Article

M Oldham, H Sakhalkar, T Oliver, GA Johnson, M Dewhirst, Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography. J Biomed Opt. Mar-Apr;13(2):021113, 2008. Free PMC article or if have access, through SPIE Digital Library

AE Petiet, MH Kaufman, MM Goddeeris, J Brandenburg, SA Elmore, GA Johnson, High-resolution magnetic resonance histology of the embryonic and neonatal mouse: a 4D atlas and morphologic database, Proc Natl Acad Sci U S A. 105(34):12331-12336, 2008. Supplemental data Free PMC article and full text available from journal

Duke news release: Anatomy of Developing Mice

AA Sharief, A Badea, AM Dale, GA Johnson, Automated segmentation of the actively stained mouse brain using multi-spectral MR microscopy, NeuroImage 39( 1): 136-1451, 2008, Free PMC article and if have access, available through Elsevier Full Text Article

S Shofer, C Badea, Y Qi, E Potts , W Foster, GA Johnson, A microCT analysis of murine lung recruitment in bleomycin-induced lung injury, Journal of Applied Physiology, 105(2): 669-677, 2008. Free PMC article or if have access, final version available through journal

LW Hedlund and T Gluckman, Basics of Small Animal Handling for In Vivo Imaging, book chapter in: Textbook of Molecular Imaging in Oncology, Martin Pomper, Juri Gelovani (Eds), Chapter 24, pp. 377-390, in: Molecular Imaging in Oncology, Martin Pomper, Juri Gelovani (Eds,), Informa Healthcare, New York, NY, October 2008.

2007

Alexandra Badea, Anjum Ali Sharief, Anders M Dale, G Allan Johnson, Morphometric analysis of the C57BL/6J mouse brain, NeuroImage 37(3): 683–693, 2007, Free PMC article of if have access, available through Elsevier Full Text Article

Alexandra Badea, Peter J. Nicholls, GA Johnson, and William C. Wetsel, Neuroanatomical phenotypes in the Reeler mouse, NeuroImage 34(4): 1363-1374, February 15, 2007. Supplemental data Free PMC article or if have access through Elsevier Full Text Article

Cristian T. Badea, Laurence W. Hedlund, Ming De Lin, Julie S. Boslego Mackel, Ehsan Samei, GA Johnson, Tomographic digital subtraction angiography for lung perfusion estimation in rodents, Medical Physics 34(5): 1546-1555, 2007. Free PMC article or if have access through journal

Cristian T Badea, Laurence W. Hedlund, Julie F. Boslego Mackel, Lan Mao, Howard A. Rockman, GA Johnson, Cardiac micro-CT for morphological and functional phenotyping of MLP null mice, Molecular Imaging, 6(4):261-268, 2007. Free PMC article

Bastiaan Driehuys, Laurence W. Hedlund, Imaging techniques for small animal models of pulmonary disease: MR microscopy, Toxicologic Pathology 35(1): 49-58, 2007. Free PMC article and if have access through SAGE journals online

Bastiaan Driehuys, Julia Walker, Jim Pollaro, Gary P. Cofer, Nilesh Mistry, David Schwartz, GA Johnson, 3He MRI in mouse models of asthma, Magn Reson Med 58(5):893-900, 2007. Free PMC article and if have access through Wiley Online Library

KB Ghaghada, KHJ Bockhorst, S Mukundan, Jr, AV Annapragada, PA Narayana, High-resolution vascular imaging of the rat spine using liposomal blood pool MR agent, American Journal of Neuroradiology, 28(1):48-53, 2007. Free PMC article

Y Jiang, JM Guccione, MB Ratcliffe, EW Hsu, Transmural heterogeneity of diffusion anisotropy in the sheep myocardium characterized by MR diffusion tensor imaging, American Journal of Physiology-Heart and Circulatory Physiology, 293(4): H2377-2384, 2007. Free article from journal

GA Johnson, A Ali-Sharief, A Badea, J Brandenburg, G Cofer, B Fubara, S Gewalt, LW Hedlund, L Upchurch, High-throughput morphologic phenotyping of the mouse brain with magnetic resonance histology, NeuroImage 37(10: 82-89, 2007. Supplementary data Free PMC article and if have access, through Elsevier Full Text Article

M Nahrendorf, C Badea, L Hedlund, J-L Figueiredo, D Sosnovik, GA Johnson, R Weissleder, High resolution imaging of murine myocardial infarction with delayed enhancement and cine micro-CT, Am J Physiol Heart Circ Physiol 292:3172-3178, 2007. Supplemental data Free PMC article or final version through journal

A Petiet, LW Hedlund, GA Johnson, Staining methods for magnetic resonance microscopy of the rat fetus, J Magn Reson Imag, 25:1192-1198, 2007. Free PMC article or if have access through Wiley Online Library

AM Ponce, BLViglianti, D Yu, PS Yarmolenko, CR Michelich, J Woo, MB Bally, MW Dewhirst, Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects, J National Cancer Institute 99(1): 53-63, January 3, 2007.

HE Rice, EW Hsu, H Sheng, DA Evenson, AJ Freemerman, KM Safford, JM Provenzale, DS Warner, GA Johnson, SPIO-labeling and transplantation of adipose-derived stem cells in MCAO-injured mice, AJR Am J Roentgenol. 188(4):1101-8, April 2007. Free full text through journal

Scott Shofer, Cristian Badea, Scott Auerbach, David Schwartz, GA Johnson, A microCT-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice, Experimental Lung Research 33:169–183, 2007. Free PMC article and also available through Informa Healthcare access free text

Jiayu Song Qing H. Liu, GA Johnson, Cristian T. Badea, Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro-CT, Medical Physics 34(11): 4476-4483, 2007. Free PMC article

Arthur W. Wetzel, Cristian T. Badea, Stuart M. Pomerantz, Nilesh Mistry, Démian Navea, GA Johnson, Measurement and modeling of 4D live mouse heart volumes from CT time series, Videometrics IX, (Eds. J-Angelo Beraldin, Fabio Remondino, Mark R. Shortis, Proc. of SPIE-IS&T Electronic Imaging, SPIE Vol. 6491, 64910J-1–64910J-7, 2007.

2006

A Ali Sharief, GA Johnson, Enhanced T2 contrast for MR histology of the mouse brain, Magn Reson Med 56(4):717–725, 2006. pdf

AWARD WINNER "Best Publication of 2006" SE chapter of American Association of Physicists in Medicine: CT Badea, LW Hedlund, MD Lin, JF Boslego, GA Johnson, Tumor imaging in small animals with a combined micro-CT / micro-DSA system using iodinated conventional and blood pool contrast agents, Contrast Media and Molecular Imaging, 1(4):153-164, July/August 2006. pdf

CT Badea, E Bucholz, LW Hedlund, HA Rockman, GA Johnson, Imaging methods for morphological and functional phenotyping of the rodent heart, Toxicologic Pathology 34(1):111-117, 2006. pdf

JE Bowsher, DM DeLong, TG Turkington, RJ Jaszczak, Aligning emission tomography and MRI images by optimizing the emission-tomography image reconstruction objective function, IEEE Transactions on Nuclear Science, 53(3): 1248-1258, 2006. pdf

B Driehuys, Toward molecular imaging with xenon MRI, Science 5798: 432-433, October 20, 2006. pdf

B Driehuys, GP Cofer, J Pollaro, J Boslego Mackel, LW Hedlund, GA Johnson, Imaging alveolar-capillary gas transfer using hyperpolarized 129Xe MRI, PNAS, 103(48): 18278-18283, 2006. pdf

TA Jaffe , RC Nelson , GA Johnson , ER Lee , TT Yoshizumi , CR Lowry, AB Bullard, DM DeLong, EK Paulson, Optimization of multiplanar reformations from isotropic data sets acquired with 16-detector row helical CT scanner, Radiology 238(1):292-299, Jan 2006. pdf

MD Lin, E Samei, CT Badea, TT Yoshizumi, GA Johnson, Optimized radiographic spectra for small animal digital subtraction angiography, Medical Physics, 33(11): 4249-4257, November 2006. pdf

Jing Mi, Shiva Sarraf-Yazdi, Xiuwu Zhang, Yiting Cao, MW Dewhirst, CD Kontos, CY Li, BM Clary. A comparison of anti-angiogenic therapies for the prevention of liver metastases, Journal of Surgical Research, 131(1): 97-104, March 2006.

Nilesh N. Mistry, Edward W. Hsu, Retrospective distortion correction for 3D MR diffusion tensor microscopy using mutual information and fourier deformations Magn Reson Med 56 (2):310-316 (2006). link to Wiley Online Library

S Mukundan, Jr., KB Ghaghada, CT Badea, CY Kao, LW Hedlund, JM Provenzale, GA Johnson, E Chen, RV Bellamkonda, A Annapragada, A liposomal nanoscale contrast agent for preclincal CT in mice, Am J Roentgenology, 186:300–307, February 2006. link to journal

Mark Oldham, Harshad Sakhalkar, Tim Oliver, Ying Min Wang, John Kirkpatrick, Yiting Cao, Cristian Badea, G. Allan Johnson, Mark Dewhirst, Three-dimensional imaging of xenograft tumors using optical computed and emission tomography, Medical Physics 33(9): 3193-3202, 2006. Google docs

Benjamin L. Viglianti, Ana M. Ponce, Charles R. Michelich, Daohai Yu, Sheela A. Abraham, Linda Sanders, Pavel S. Yarmolenko, Thies Schroeder, James R. MacFall, Daniel P. Barboriak, O. Michael Colvin, Marcel B. Bally, Mark W. Dewhirst, Chemodosimetry of in-vivo tumor liposomal drug concentration using MRI, Magn Reson Med 56(5): 1011–1018, 2006. Wiley Online Library

Y Wang, F Yuan, Delivery of viral vectors to tumor cells: Extracellular transport, systemic distribution, and strategies for improvement. Annals of Biomedical Engineering. Invited paper. 2006.

H Yuan, T Schroeder, JE Bowsher, LW Hedlund, T Wong, MW Dewhirst, Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-Diacetyl-Bis(N4-Methylthiosemicarbazone), Journal of Nuclear Medicine, J Nucl Med 47:989–998, 2006. pdf

2005

AA Ali, AM Dale, A Badea, GA Johnson, Automated segmentation of neuroanatomical strructures in multispectral MRM of the mouse brain. NeuroImage 27(2):425-35, August 2005. pdf

C Badea, B Fubara, LW Hedlund, GA Johnson, 4D cardiac micro-CT of the mouse heart, Molecular Imaging, 4(2): 110-116, (April-June) 2005. pdf

BT Chen, AT Yordanov, GA Johnson, Ventilation-synchronous MR microscopy of pulmonary structure and ventilation in mice, Magn Reson Med 53(1): 69-75, 2005. pdf

Bin Chen, Edward W Hsu, Noise removal in MR diffusion tensor imaging, Magn Reson Med 54(2):393-407, 2005. pdf

M Cyr, MG Caron, GA Johnson, A Laakso, Magnetic resonance imaging at microscopic resolution reveals subtle morphological changes in a mouse model of dopaminergic hyperfunction, NeuroImage, 26: 83-90,2005. pdf

LW Hedlund, GA Johnson, Morphology of the small animal lung using MR microscopy, Proceedings of the American Thoracic Society 2(6): 481-483, 2005. pdf

Y Jiang, EW Hsu, Accelerating MR diffusion tensor imaging via filtered reduced encoding projection reconstruction, Magn Reson Med 53(1): 93-102, 2005. pdf

W Maï, CT Badea, CT Wheeler, LW Hedlund, GA Johnson, Effects of breathing and cardiac motion on the spatial resolution in microscopic imaging of rodents, Magn Reson Med 53(4): 858-865, 2005. pdf

MW Tengowski, P Sutovsky, LW Hedlund, DJ Guyot, JE Burkhardt, WE Thompson, M Sutovsky, GA Johnson, Reproductive cytotoxicity is predicted by MR microscopy and confirmed by ubiquitin–proteasome immunohistochemistry in a theophylline-induced model of rat testicular and epididymal toxicity, Microscopy and Microanalysis 11(04): 300-312, 2005. access through Cambridge journals

JC Walker, JM Guccione, Y Jiang, P Zhang, AW Wallace, EW Hsu, MB Ratcliffe, Helical myofiber orientation after myocardial infarction and left ventricular surgical restoration in sheep.  J Thorac Cardiovasc Surg. 129(2):382-90, Feb 2005. access through Elsevier full text article

2004

C Badea, R Gordon, Experiments with the nonlinear and chaotic behaviour of the multiplicative algebraic reconstruction technique (MART) algorithm for computed tomography, Phys Med Biol, 49(8): 1455-1474, 2004. access through IOP Science

C Badea, L. Hedlund, GA Johnson, Micro-CT with respiratory and cardiac gating, Med Phys 31(12) 3324-3329, 2004. pdf

ACS Brau, LW Hedlund, GA Johnson, Cine magnetic resonance microscopy of the rat heart using cardiorespiratory-synchronous projection reconstruction imaging,  J Magn Res Img 20: 31-38, 2004. pdf

BT Chen, GA Johnson, Dynamic lung morphology of methacholine-induced heterogeneous bronchoconstriction, Magn Reson Med, 52(5): 1080-1086, 2004. pdf

C Gilchrist, J Xia, L Setton, E Hsu, High-resolution determination of soft tissue deformation using MRI and first-order texture correlation. IEEE-Trans Med Imaging, 23(5): 546-553, May 2004. pdf

Y Jiang, K Pandya, O Smithies, EW Hsu, Three-dimensional diffusion tensor microscopy of fixed mouse hearts, Magn Reson Med 52:453–460, 2004. pdf

RR Maronpot, RC Sills, GA Johnson, Applications of MR microscopy, Toxicol Pathol, 32 (Suppl. 2):42–48, 2004. pdf

WP Segars, BMW Tsui, EC Frey, GA Johnson, SS Berr, Development of a 4-D digital mouse phantom for molecular imaging research, Mol Imag Biol, 6(3): 149-159, 2004. pdf

RC Sills, DL Morgan, DW Herr, PB Little, NM George, TV Ton, NE Love, RR Maronpot, GA Johnson, Contribution of MR microscopy in the 12-Week neurotoxicity evaluation of carbonyl sulfide in Fischer 344 rats, Toxicol Path, 32:501–510, 2004. pdf

W Taylor, E Hsu, R Krishnan, J MacFall, Diffusion tensor imaging: background, potential and utility in psychiatric research, Biol Psych 55: 201-207, 2004. access through Elsevier Full Text Article

BL Viglianti, SA Abraham, CR Michelich, PS Yarmolenko, JR MacFall, MB Bally, MW Dewhirst, In-vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: illustration of targeted delivery, Magn Reson Med 51:1153-1162, 2004. pdf

ER Ward, LW Hedlund, WC Kurylo, CT Wheeler, GP Cofer, MW Dewhirst, LB Marks, Z Vujaskovic, Proton and hyperpolarized Helium MR imaging of radiation-induced lung injury in rats,, Int J Rad Oncol Biol Phys 58(5): 1562–1569, 2004. pdf

X Zhang, M Tengowski, L Fasulo, S Botts, SA Suddarth, Measurement of fat/water ratios in rat liver using 3D three-point Dixon MRI, Magn Reson Med 51:697-702, 2004. pdf

2003

BT Chen, ACS Brau, GA Johnson, Measurement of regional lung function in rats using hyperpolarized 3He dynamic MRI, Magn Reson Med 49: 78-88, 2003. pdf

AK Gupta, RC Nelson, GA Johnson, EK Paulson, DM Delong, TT Yoshizumi. Optimization of 8-element multi-detector row helical CT technology for evaluation of the abdomen. Radiol 227(3): 739-45, 2003. pdf

X Zhang, TM Yelbuz, GP Cofer, MA Choma, ML Kirby, Improved preparation of chick embryonic samples for MR microscopy, Magn Reson Med 49(6): 1192-1195, 2003. pdf

TM Yelbuz, KL Waldo, X Zhang, M Zdanowica, J Parker, TL Creazzo, GA Johnson, ML Kirby, Myocardial volume and organization are changed by failure of addition of secondary heart field myocardium to the cardiac outflow tract, Developmental Dynamics 228: 152-160, 2003. pdf

TM Yelbuz, X Zhang, MA Choma , HA Stadt, M Zdanowicz, GA Johnson, ML Kirby, Approaching cardiac development in three dimensions by magnetic resonance microscopy, Circulation 108: e154-e155, December 2, 2003. pdf

2002

KJL Burg, M Delnomdedieu, RJ Beiler, CR Culberson, KG Greene, CR Halberstadt, WD Holder, Jr., AB Loebsack, WD Roland, GA Johnson. Application of MR microscopy to tissue engineering: a polylactide model, J Biomed Res 61(3): 380-390, 2002. pdf

ACS Brau, CT Wheeler, LW Hedlund, GA Johnson, The fiber-optic stethoscope: a cardiac monitoring and gating system for magnetic resonance microscopy. Magn Reson Med 47, 314-321, 2002. pdf

PJ Gareau, AC Wymore, GP Cofer, GA Johnson, Imaging inflammation: direct visualization of perivascular cuffing in EAE by MR microscopy, JMRI 16(1): 28-36, 2002. pdf

LW Hedlund, GA Johnson, Mechanical ventilation for imaging the small animal. ILAR J 43(3): 159-174, 2002. pdf

GA Johnson, GP Cofer, SL Gewalt, LW Hedlund, Morphologic phenotyping with magnetic resonance microscopy: the visible mouse. Radiology 222, 789-793, 2002. pdf

GA Johnson, GP Cofer, B Fubara, SL Gewalt, LW Hedlund, RR Maronpot, Magnetic resonance histology for morphologic phenotyping, JMRI 16: 423-429, 2002. pdf

GA Johnson, The Imaging Tower of Babel, guest editorial, Biophotonics International, p 15, Sept 2002. pdf

AL Muzikant, EW Hsu, PD Wolf, CS Henriquez, Region specific modeling of cardiac muscle: comparison of simulated and experimental potentials. Ann Biomed Eng, 30(7): 867-883, 2002. pdf

HE Möller, XJ Chen, B Saam, KD Hagspiel, GA Johnson, TA Altes, EE de Lange, H Kauczor. MRI of the lungs using hyperpolarized noble gases, Magn Reson Med 47: 1029–1051, 2002. link to article

BL Viglianti, SA Abraham, JR MacFall, MB Bally, MW Dewhirst, In-vivo monitoring of real time tissue pharmacokinetics of liposome/drug concentration using MRI: illustration of targeted delivery, Radiology 225: 647-648, Suppl. S Nov 2002. access through Wiley Online Library

SP Wolfe, EW Hsu, LM Reid, JM Macdonald. A novel multi-coaxial hollow fiber bioreactor for adherent cell types. Part 1: hydrodynamic studies, Biotech and Bioengineering, 77: 83-90, 2002. pdf

2001

EW Hsu, CS Henriquez, Myocardial fiber orientation mapping using reduced-encoding diffusion tensor imaging, J Cardiovascular Magn Reson  3(4): 339-347, 2001.

EW Hsu, DL Buckley, JD Bui, SJ Blackband, JR Forder, Two-component diffusion tensor MRI of isolated perfused hearts. Magn Reson Med 45: 1039-1045, 2001. access through Wiley Online Library

GA Johnson, GP Cofer, LW Hedlund, RR Maronpot, SA Suddarth, Registered 1H and 3He MR microscopy images of the lung. Magn Reson Med  45: 365-370, 2001.

SJ Kelly, M Delnomdedieu, MI Oliverio, LD Williams, MGP Saifer, MR Sherman, TM Coffman, GA Johnson, MS Hershfield, Diabetes insipidus in uricase-deficient mice: a model for evaluating therapy with poly(ethylene glycol)-uricase. J Am Soc Nephrol 12: 1001-1009, 2001. free access through journal

HE Moller, LW Hedlund, XJ Chen, MR Carey, MS Chawla, CT Wheeler, GA Johnson, Measurements of hyperpolarized gas properties in the lung, Part III: 3He T1. Magn Reson Med 45: 421-430, 2001. access through Wiley Online Library

2000

H Benveniste, KR Kim, LW Hedlund, JW Kim, AH Friedman, Cerebral hemorrhage and edema following brain biopsy in rats: significance of mean arterial pressure, J Neurosurg 92: 100-107, 2000.

H Benveniste, KR Kim, L Zhang and GA Johnson,  MR microscopy of the C57BL mouse brain, NeuroImage 11: 601-611, 2000. acces through Elsevier Full Text Article

MS Chawla, XJ Chen, GP Cofer, LW Hedlund, MB Kerby, T Ottoboni, GA Johnson, Hyperpolarized 3He microspheres as a novel vascular signal source for MRI, Magn Reson Med 43: 440-445, 2000. access through Wiley Online Library

XJ Chen, LW Hedlund, HE Möller, MS Chawla, RR Maronpot, GA Johnson, Detection of emphysema in rat lungs using magnetic resonance measurements of 3He diffusion, PNAS 97: 11478-11481, 2000. access through journal

LW Hedlund, GP Cofer, SJ Owen, GA Johnson, MR-compatible ventilator for small animals: computer-controlled ventilator for proton and noble gas imaging, Magn Reson Imag 18: 753-759, 2000. pdf

LW Hedlund, HE Möller, XJ Chen, MS Chawla, GP Cofer, GA Johnson, Mixing oxygen with hyperpolarized 3He for small-animal lung studies, NMR in Biomed 13: 202-206, 2000. pdf

DS Lester, PS Pine, M Delnomdedieu, JN Johannessen, GA Johnson, Virtual neuropathology: three-dimensional visualization of lesion due to toxic insult, Toxicol Pathol 28: 100-104, 2000. if have access through Sage Publications

AC Nugent, GA Johnson, T1rho imaging using magnetization-prepared projection encoding, Magn Reson Med 43: 421-428, 2000. access through Wiley Online Library

MI Oliverio, M Delnomdedieu, CF Best, P Li, M Morris, GA Johnson, O Smities, TM Coffman, Abnormal water metabolism in mice lacking the type 1A receptor for angiotensin II, Am J Physiol 278: F15-F82, 2000. access through journal

R Weissleder, A Moore, U Mahmood, R Bhorade, H Benveniste, EA Chiocca, JP Basilion, In vivo MR imaging of transgene expression, Nature Medicine, 6, 351-5, 2000. access through journal

1999

H Benveniste, G Einstein, K Kim, C Hulette, GA Johnson, Detection of neuritic plaques in Alzheimer's Disease by MR microscopy, PNAS USA, 96: 14079-14084, 1999. Free PMC article

H Benveniste, H Qiu, LW Hedlund, PC Hüttemeier, SM Steele, GA Johnson, In vivo diffusion-weighted MR microscopy of rat spinal cord: effect of ischemia and intrathecal hyperbaric 5% lidocaine, Regional Anesthesiology and Pain Medicine, 24 (4): 311-318, 1999. access through Science Direct

XJ Chen, HE Möller, MS Chawla, GP Cofer, B Driehuys, LW Hedlund, GA Johnson,  Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part I: diffusion coefficient, Magn Reson Med 42: 721-728, 1999. access through Wiley Online Library

XJ Chen, HE Möller, MS Chawla, GP Cofer, B Driehuys, LW Hedlund, JR MacFall, GA Johnson, Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part II: T2*, Magn Reson Med 42: 729-737, 1999. access through Wiley Online Library

LW Hedlund, MS Chawla, XJ Chen, GP Cofer, HE Möller, GA Johnson, MR microscopy in small animal models of pulmonary disease, Euro Radiol, 9, 32, 1999.

EW Hsu, LA Setton, Diffusion tensor microscopy of the intervertebral disc anulus fibrosus, Magn Reson Med 41(5): 992-9, 1999. access through Wiley Online Library

DS Lester, JN Johannessen, PS Pine, GN McGregor, GA Johnson, Virtual neuropathology: A new approach to preclinical pathology using MR imaging microscopy, Spectroscopy 14: 17-22, 1999.

DS Lester, RC Lyon, GN McGregor, RT Engelhardt, LC Schmued, GA Johnson, JN Johannessen, 3-dimensional visualization of lesions in rat brain using MR microscopy, NeuroReport 10(4): 737-741, 1999.

LA Setton, F Guilak, EW Hsu, TP Vail, Biomechanical factors in tissue engineered meniscal repair, Clin Ortho & Related Res 367 Suppl: S254-72, 1999.

M Thorne, AN Salt, JE DeMott, MM Henson, OWJ Henson, SL Gewalt, Cochlear fluid space dimensions for six species derived from reconstrcutions of three-dimensional MR images, The Laryngoscope, 109, 1661-1668, 1999. access through Wiley Online Library

M Viallon, GP Cofer, SA Suddarth, HE Möller, XJ Chen, MS Chawla, LW Hedlund, Y Cremillieux, GA Johnson, Functional MR microscopy of the lung with hyperpolarized 3He, Magn Reson Med 41: 787-792, 1999. access through Wiley Online Library

1998

H Benveniste, H Qiu, LW Hedlund, F D´Ercole, GA Johnson, Spinal cord neural anatomy in rats examined by in vivo magnetic resonance microscopy. Regional Anesthesia 23(6): 589-599, 1998.

MS Chawla, XJ Chen, HE Möller, GP Cofer, CT Wheeler, LW Hedlund, GA Johnson, In vivo MR vascular imaging using laser-polarized 3He microbubbles. Proceedings of the National Academy of Sciences USA 95, 10832-10835, 1998. if have access, through journal or Free PMC article

XJ Chen, MS Chawla, LW Hedlund, HE Moller, JE MacFall, GA Johnson: MR microscopy of lung airways with hyperpolarized 3He. Magn Reson Med 39(1):79-84, 1998. access through Wiley Online Library

XJ Chen, Chawla MS, Hedlund LW, Moller HE, Johnson GA, Hyperpolarized 3He NMR lineshape measurements in the live guinea pig lung. Magn Reson Med 40, 61-65, 1998. access through Wiley Online Library

M Delnomdedieu, LW Hedlund, RR Maronpot, GA Johnson, Magnetic resonance microscopy and histopathology: comparative approach of bromobenzene-induced hepatoxicity in the rat. Hepatology. 27, 526-532, 1998. access through Wiley Online Library

EW Hsu, LW Hedlund, JR MacFall, fMRI of rat somatosensory cortex: effects of hyperventilation. Magn Reson Med 40(3): 421-426, 1998. access through Wiley Online Library

EW Hsu, SB Reeder, JR MacFall, Single-shot, variable flip-angle slice-selective excitation with 4 gradient-modulated adiabatic half-passage segments. Magn Reson Med. 40(2), 334-340, 1998. access through Wiley Online Library

EW Hsu, AL Muzikant, SA Matulevicius, RC Penland, CS Henriquez, Magnetic resonance myocardial fiber orientation mapping with direct histological correlation. AJP: Heart and Circulatory Physiology 274,1627-1634, 1998. if have access, available through journal

GY Huang, A Wessels, BR Smith, KK Linask, JL Ewart, CW Lo, Alteration in connexin 43 gap junction gene dosage impairs conotruncal heart development. Developmental Biology 198, 32-44, 1998. access through Elsevier full text article

GA Johnson, LW Hedlund, JR MacFall A new window into the lung. Physics World 35-38, November 1998.

HE Moller, XJ Chen, MS Chawla, B Driehuys, LW Hedlund, GA Johnson, Signal dynamics in magnetic resonance imaging of the lung with hyperpolarized noble gases. Journal of Magnetic Resonance, 135: 133-143, 1998.

H Qiu, LW Hedlund, MR Neuman, CR Edwards, RD Black, GP Cofer, GA Johnson. Measuring the progression of foreign body reaction to silicone implants using in vivo MR microscopy. IEEE Transactions on Biomedical Engineering 45, 921-927, 1998. access through IEEE XPlore

BR Smith, MD Shattuck, LW Hedlund, GA Johnson, Time-course imaging of rat embryos in utero with magnetic resonance microscopy. Magn Reson Med, 39(4): 673-677, 1998. access through Wiley Online Library

SA Suddarth, A method for matching high-temperature superconducting resonators used for NMR signal pickup at 400 MHz. IEEE Transactions in Biomedical Engineering, 45 (8): 1061-1066. 1998. access through IEEE XPlore

X Zhou, ZP Liang, SL Gewalt, GP Cofer, PC Lauterbur, GA Johnson, A fast spin echo technique with circular sampling. Magn Reson Med 39: 23-27, 1998.

1997

SE Hurlston, GP Cofer, GA Johnson: Optimized receiver coils for increased SNR in MR microscopy. Intl J of Imag Systems and Tech 8:277-284, 1997.

GA Johnson, XJ Chen, G Cates, GP Cofer, B Driehuys, LW Hedlund, W Happer, B Saam, MD Shattuck, J Swartz: Dynamics of magnetization in hyperpolarized gas MRI of the lung. Magn Reson Med  38: 66-71, 1997. access through Wiley Online Library

GA Johnson, H Benveniste, RT Engelhardt, H Qiu, LW Hedlund: “Magnetic Resonance microscopy in basic studies of brain structure and function.” In: Imaging Brain Structure and Function: Emerging Technologies in the Neurosciences, Eds. D Lester, C Felder, EN Lewis, NY Academy of Sciences, New York, NY: pp 139-148, 1997. access through Wiley Online Library

JS MacFall, GA Johnson: Root form and function meshed by MRI. Plant Physiol 114(3):20002 Suppl. July, 1997.

H Qiu, LW Hedlund, SL Gewalt, H Benveniste, TM Bare, GA Johnson: Progression of a focal ischemic lesion in rat brain during treatment with a novel Glycine/NMDA antagonist: an in vivo 3D diffusion-weighted MR microscopy study. JMRI 7(4):739-744, 1997. access through Wiley Online Library

H Qiu, GP Cofer, LW Hedlund, GA Johnson: Automated feedback control of body temperature for small animal studies with MR microscopy.  IEEE Trans Biomed Eng 44:1107-1113, 1997. pdf

MD Shattuck, RP Behringer, J Georgiadis, GA Johnson: Convection and flow in porous media, I: Visualization by magnetic resonance imaging. J Fluid Mechan 332:215-245, 1997.

MD Shattuck, SL Gewalt, GH Glover, LW Hedlund, GA Johnson: MR microimaging of the lung using volume projection encoding. Magn Reson Med 38(6):938-942, 1997. access through Wiley Online Library

RM Vandemark, ME Fay, FR Porter, GA Johnson: Digital image-intensifier radiography at a level 1 trauma center. AJR 168(4):944-946, 1997. access through journal

C Zimmer, SCJ Wright, RT Engelhardt, GA Johnson, XO Breakefield, R Weissleder: Tumor cell endocytosis (TCE) imaging facilitates delineation of the glioma-brain interface. Exper Neurol 143:61-69, 1997. access through Elsevier full text article

 

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