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The Center for In Vivo Microscopy (CIVM) develops methods for small animal imaging and applies the tools and techniques we develop to important biomedical questions. The Center and our faculty have been fortunate to have funding support to create an imaging program that spans a broad range of technologies and applications.

 

 

FUNDING

CIVM receives funding from NIH / National Institute of Biomedical Imaging and Bioengineering (NIBIB), as one of the national Biomedical Technology Resource Centers (P41 EB015897) that covers 5 research core areas with these faculty directors:

  • GA Johnson/C Liu - Core A: Expand Utility of MR Microscopy
  • CT Badea - Core B: Extend Micro-CT / Image Reconstruction for Functional Imaging
  • B Driehuys - Core C: Broaden Applicability of Hyperpolarized MR
  • M Fischer/W Warren: Core D: Optical Imaging
  • A Badea - Core E: Visual Informatics

The faculty also receive additional support from NIH or other funding agencies as PIs, co-investigators, investigators, and mentors.

G ALLAN JOHNSON PhD - PI, Director of P41 grant listed above, and co-PI on P41 Core A

Investigator or Co-Investigator on these grants:

DoD CDMRP PT120133     D Agoston (PI)
Mechanism and Biomarkers of Degenerative Conditions After Repeated Mild Traumatic Brain Injury (rmTBI)

Susan G. Komen for the Cure IIR13263571    D Kirsch (PI) Minimizing Cardiac Injury from Ionizing Radiation During Breast Cancer Therapy

National Multiple Sclerosis Society RG-4723A1/1    Liu (PI) Improving the Diagnosis of Multiple Sclerosis with In Vivo MR Imaging of Myelin and Iron

NIH/NIMH 5R01-MH096979 02    C Liu (PI) Ultra-resolution imaging of brain Circuitry and its Development in Mental Health

ALEXANDRA BADEA PhD - director of P41 Core E, and PI on grant below:

NIH/NIA 1K01-AG041211-01A     Quantitative MR Microscopy of Phenotypic Biomarkers in Alzheimer's Disease

CRISTIAN BADEA PhD - P41 Core B director, and PI of the grant below:

NIH/NCI R01 CA196667    Badea (PI) Development of a New Generation Micro-CT imaging for Functional and Molecular Imaging

Co-investigator on these grants:

Susan G. Komen for the Cure IIR13263571   D Kirsch (PI) Minimizing Cardiac Injury from Ionizing Radiation During Breast Cancer Therapy

NIH/NCI 1R21 CA175839-01A1    D Kirsch (PI) Defining the Cellular Target of Radiation Therapy

BASTIAAN DRIEHUYS PhD- director of P41 Core C, and PI on grants below:

NIH/NHLBI R01HL126771    Driehuys (PI) Using MRI To Visualize Regional Therapy Response In Idiopathic Pulmonary Fibrosis

NIH/NHLBI 1R01HL105643    B Driehuys (PI) Early Detection of Changes in Pulmonary Gas Exchange by Hyperpolarized 129Xe MRI

NIH/NCI 1R01-CA142842   B Driehuys (co-PI) Branca (co-PI) Sensitive and Specific Molecular Imaging of Pulmonary Nodules

Gilead Sciences   Driehuys (PI) Quantitative 129Xe Gas Exchange MRI for Idiopathic Pulmonary Fibrosis

Co-investigator:

NIH/NHLBI R01 HL111294   C Charles (PI) B Driehuys (Co-investigator) Gas Exchange Imaging in Rodent Models of Smoke Exposure

MARTIN FISCHER PhD - Co-director of P41 Core D

CHUNLEI LIU PhD - Co-director P41 Core A, and PI on these grants:

NIH/NHLBI 1R2 HL122759-01   C Liu (PI) High-resolution in vivo and non-invasive imaging of myocardial fibers

NIH/NIMH 5R01-MH096979 02    C Liu (PI) Ultra-resolution imaging of brain Circuitry and its Development in Mental Health

National Multiple Sclerosis Society RG-4723A1/1    Liu (PI) Improving the Diagnosis of Multiple Sclerosis with In Vivo MR Imaging of Myelin and Iron

WARREN S. WARREN PhD - Co-director of P41 Core D, and PI on these grants:

NIH/NIBIB 5R01 EB002122-22    WS Warren (PI)
Intermolecular Multiple-Quantum Coherence Effects in MRI

NIH/NCI 5R01 CA166555-02    WS Warren (PI)
Improving Melanoma Diagnosis with Pump-Probe Optical Imaging

 

Some faculty members hold joint appointments and are mentors to graduate students in Biomedical Engineering, Medical Physics, and the Medical Scientist Training Program with these programs supported by training grants:

NIH/NIBIB 5T32 EB001040-08   K Nightingale (PI) Training in Medical Imaging

NIH/NIGMS 5T32 GM007171-40   C Kontos (PI)  Medical Scientist Training Program

Also, some of the Center's cancer projects are supported by the Duke Cancer Center Support Grant (CCSG) (NCI P30 CA014236), PI Michael Kastan

 
 

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