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A collaboration between Nian Wang, PhD in the Department of Radiology and Matthew Hilton PhD in the Departments of Orthopaedic Surgery and Cell Biology has produced the highest resolution diffusion tensor images (DTI) of articular cartilage ever obtained in the rat knee. DTI which has been used extensively in neurologic models has been adapted to display the underlying fiber structure in the meniscus promising new insight into the biomechanics of cartilage and destructive diseases such as arthritis. The striking images were awarded the cover of Magnetic Resonance in Medicine. Wang N et al, Diffusion tractography of the rat knee at microscopic resolution, Magnetic Resonance in Medicine, 2019; 81:3775-3786
High-Resolution DTI of Rat Knee articular cartilage
Courtesy Nian Wang PhD
Diffusion tractography of control (B6) mouse (left) and BTBR mouse- a model of Autism spectrum disorder Courtesy Nian Wang, Ph.D.