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Nicholas Befera, MD - Radiology Resident (with Cristian Badea and G. Allan Johnson)

4D cardiac imaging the mouse using micro-SPECT and micro-CT

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PURPOSE OF THIS STUDY: Compare 4D micro-CT and 4D micro-SPECT for functional imaging in C57BL/6 mice

Orthogonal views of the mouse heart in diastole acquired with micro-SPECT (top row) and micro-CT (bottom row).
Dynamic 4D micro-SPECT (top) and micro-CT (bottom) throughout the cardiac cycle (10 time bins).

Segmentation of the left ventricle using Vitrea software for micro-SPECT (top) and micro-CT (bottom) datasets.