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Journal club
Wednesdays at noon-1 PM
Room 162
Bryan Research Building
Info: 919 684-7758
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Duke Center for In Vivo Microscopy (CIVM) is an NIH/NCRR National Biomedical Technology Research Center that develops medical technologies with applications for small animal imaging at microscopic resolution.
As an NCI Small Animal Imaging Resource Program, we help researchers apply these technologies to cancer research.
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We offer 2T, 7T, and 9.4T MR microscopy, micro-CT, micro x-ray, ultrasound, and optical imaging technologies. For details about our imaging facilities, CLICK HERE. To initiate a project with the Center, CLICK HERE to go to our collaboration link.
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CIVM continues to expand our range of technical capabilities and applications, such as these examples:
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3He MR lung imaging
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4D micro-CT of the mouse heart
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4D heart analysis
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2 positions available |
Assistant Professor |
Post-doctoral Associate |
| e-mail for more information or call 919 684-7758 |
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2009 department publications
| A Badea, RW Williams, GA Johnson, Genetic dissection of the mouse brain using high-field magnetic resonance microscopy, Neuroimage. 2009 May 1; 45(4):1067-1079, http://dx.doi.org/10.1016/j.neuroimage.2009.01.021. |
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A Mackenzie-Graham SK Tiwari-Woodruff, G Sharma, C Aguilar, KT Vo, LV Strickland, L Morales, B Fubara, M Martin, RE Jacobs, GA Johnson, AW Toga, RR Voskuhl, Purkinje cell loss in experimental autoimmune encephalomyelitis, NeuroImage, 48(4): 637-652, 2009 |
| A Badea, GA Johnson, R Williams, Genetic dissection of the mouse CNS using magnetic resonance microscopy, invited paper: Current Opinion in Neurology 22:379–386, 2009 |
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SE Parnell, SK O’Leary Moore, EA Godin, DB Dehart, BW Johnson, GA Johnson, et al, Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8, Alcoholism: Clinical and Experimental Research 33(4): 1001-1011, 2009 |
| M Hyeok Bae, R Pan, T Wu, A Badea, Automated segmentation of mouse brain images using extended MRF, Neuroimage 46(3): 717-725, 2009 |
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J Song, Y Liu, SL Gewalt, GCofer, GA Johnson, QH Liu, Least-square NUFFT methods applied to 2-D and 3-D radially encoded MR image reconstruction, IEEE Transactions on Biomedical Engineering, 56(4):1134-1142, 2009 |
| K Frinkley Bing, GP Howles, Y Qi, ML Palmeri, KR. Nightingale, Blood-brain barrier disruption using a diagnostic ultrasound scanner and Definity® in mice, Ultrasound in Medicine and Biology, 35:1298-1308, 2009 |
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AC Thomas, EN Potts, BT Chen, DM Slipetz, WM Foster, B Driehuys. A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized (3)He MRI, NMR Biomed. 22(5): 502-515, 2009 |
| Z Cleveland, H Moeller, L Hedlund, B Driehuys, Continuously infusing hyperpolarized 129Xe into flowing aqueous solutions using hydrophobic gas exchange membranes, The Journal of Physical Chemistry B, 113(37): 12489-12499, 2009. |
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X Zhang, C Badea, Effects of sampling strategy on image quality in noncontact panoramic fluorescence diffuse optical tomography for small animal imaging, Optics Express 17(7): 5125-5138, 2009 |
| B Driehuys, H Moeller, J Pollaro, Z Cleveland, LW Hedlund, MR imaging of pulmonary perfusion and Xe gas exchange in rats by intravenous injection of hyperpolarized 129Xe, Radiology 252(2): 386-393, 2009 |
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X Zhang, C Badea, M Jacob, GA Johnson, Development of a noncontact 3-D fluorescence tomography system for small animal in vivo imaging, Proc Soc Photo Opt Instrum Eng. 7191 2009 |
| GP Howles, JC Nouls, Y Qi, GA Johnson, Rapid production of specialized animal handling devices using computer-aided design and solid freeform fabrication, Journal of Magnetic Resonance Imaging, 30(2):466-471, 200. |
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You Tube—Brain Model—(K Kernstine) Each brain structure was segmented individually using Amira 6 software http://www.youtube.com/watch?v=Svh_K75AVUw |
2009 publications in press
| E Bucholz, K Ghaghada, Y Qi, S Mukundan, HA Rockman, GA Johnson, Cardiovascular phenotyping of the mouse heart using a 4d radial acquisition and liposomal Gd-DTPA-BMA, Magnetic Resonance in Medicine |
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NN Mistry, Y Qi, LW Hedlund, GA Johnson, Ventilation/perfusion imaging in a rat model of airway obstruction, Magnetic Resonance in Medicine |
| GP Howles, KB Ghaghada, Y Qi, S Mukundan, Jr., GA Johnson, High-resolution magnetic resonance angiography in the mouse using a nanoparticle blood-pool contrast agent, Magnetic Resonance in Medicine |
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A Petiet, GA Johnson, Activing staining of mouse embryos for magnetic resonance microscopy. In: TD Hewitson, IA Darby (Eds), Histology Protocols (Methods in Molecular Biology), Springer-Humana Press, Totowa, NJ, expected January 2010. |
| M Lin, CT Marshall, Y Qi, SM Johnston, CT Badea, CA Piantadosi, GA Johnson, Quantitative blood flow measurements in the small animal cardiopulmonary system using digital subtraction angiography, Medical Physics |
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X Zhang, CT Badea, GA Johnson, Three-dimensional reconstruction in free-space whole-body fluorescence tomography of mice using optically reconstructed surface and atlas anatomy, Journal of Biomedical Optics |
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